Biocatalysis and Protein Engineering Centre for Sustainable Synthesis (BioProcess)

Industrial manufacturing is at a turning point. Many conventional production routes rely on non-renewable resources, harmful chemicals and energy-intensive processes. Biocatalysis using engineered enzymes offers a proven solution.

Led by The University of Manchester, in collaboration with AstraZeneca, the Universities of Bristol and York, and leading industrial partners, the Biocatalysis and Protein Engineering Centre for Sustainable Synthesis (BioProcess IDLA) will train the next generation of scientists in the skills needed to realise the full potential of biocatalysis, protein engineering and biomanufacturing for the UK bioeconomy.

Eligibility

Applicants should have, or expect to achieve, at least a 2.1 honours degree or a master’s (or international equivalent) in a relevant science or engineering related discipline.

How to apply

Want to be considered for a Biocatalysis and Protein Engineering (BioProcess) PhD programme studentship?

Find out what you need to do before you apply and how to apply with our step-by-step guide.

Projects

Projects have been co-developed by industry and academic partners with a focus on multidisciplinary team-science that delivers solutions to real-world challenges in one of four focus areas:

  • Design and discovery of new enzyme chemistry
  • Laboratory automation and AI for accelerated protein engineering
  • Assembly of enzyme cascades and cell factories
  • Realising biotransformations at scale.

Explore available projects

Training

BioProcess aims to train the next generation of bio-innovators. Our interdisciplinary programmes prepare PhD students and researchers with the real-world skills to apply biocatalysis, protein engineering and sustainable manufacturing in industry.

We offer:

  • PhD projects co-developed with industry and aligned with real manufacturing challenges
  • Advanced theoretical and practical skills training provided by a mixture of industry and academic project partners covering structural biology; biophysical and analytical methods; computational modelling; directed evolution; process modelling and development; and digital skills
  • Access to a network of elite partners and mentors
  • A strong track record of impact, including a free online course in industrial biotechnology with over 10,000 learners to date.

Strong foundations in biocatalysis

Formerly CoEBio3, our centre has a focus on delivering solutions with real impact in pharmaceutical and chemical manufacturing with our industry partners. Our work has already enabled major industrial advances.

  • 1,000+

    Commercialised over 1,000 enzymes

    Covering 20+ reaction types, significantly expanding biocatalytic options for manufacturing.

  • Pioneered metal-free processes

    Reducing reliance on costly and hazardous precious metal catalysts.

  • Delivered high-performing biocatalysts

    Engineered industry-ready enzymes suitable for large scale pharmaceutical manufacturing.

Get in touch

If you have a question or are interested in finding out more about the BioProcess IDLA, get in touch.

Email the BioProcess IDLA

Partners

The University of Manchester logo
University of Bristol logo
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